Dr. Karl Fryxell is an associate professor in the School of Systems Biology in the College of Science.
Polesskaya, O. O. R. F. Smith and K. J. Fryxell (2006) Chronic nicotine doses down-regulate PDE4 isoforms that are targets of antidepressants in adolescent female rats. Biol. Psychiatry, 61, 56-64.
Polesskaya, O. O., K. J. Fryxell, A. D. Merchant, L. L. Locklear , K.- F. Ker, C. G. McDonald, A. K. Eppolito, L. N. Smith, T. L. Wheeler, R. F. Smith (2007) Nicotine causes age-dependent changes in gene expression in the adolescent female rat brain. Neurotoxicology & Teratology, in press.