Department of Molecular Neuroscience: Computational and experimental approaches to the biophysical and biochemical mechanisms of long term memory storage, understanding the cellular and molecular events underlying the discrimination of spatio-temporal patterns by neurons
Kim 'Avrama' Blackwell is a professor in the department of Moledular Neuroscience in the Krasnow Institute of Advanced Studies.
Sensitivity to theta-burst timing permits LTP in dorsal striatal adult brain slice. Hawes SL, Gillani F, Evans RC, Benkert EA, Blackwell KT. J Neurophysiol. 2013 Aug 7. [Epub ahead of print]
Dynamic modulation of spike timing dependent calcium influx during cortico-striatal upstates. Evans RC, Maniar YM, Blackwell KT. J Neurophysiol. 2013 Jul 10. [Epub ahead of print]
Signaling pathways involved in striatal synaptic plasticity are sensitive to temporal pattern and exhibit spatial specificity. Kim B, Hawes SL, Gillani F, Wallace LJ, Blackwell KT. PLoS Comput Biol. 2013; 9(3):e1002953.
The Effects of NMDA Subunit Composition on Calcium Influx and Spike Timing-Dependent Plasticity in Striatal Medium Spiny Neurons. Evans, Morera-Herreras, Cui, Du, Sheehan, Kotaleski, Venance, Blackwell. PLoS Comput Biol. 2012; 8:e1002493.
Subcellular Location of PKA Controls Striatal Plasticity: Stochastic Simulations in Spiny Dendrites. Oliveira, Kim, Blackwell. PLoS Comput Biol. 2012; 8:e1002383.
Colocalization of protein kinase A with adenylyl cyclase enhances protein kinase A activity during induction of long-lasting long-term-potentiation. Kim, Park, Havekes, Chay, Guercio, Oliveira, Abel, Blackwell. PLoS Comp Biol. 2011; 7: e1002084.
Modelling the molecular mechanisms of synaptic plasticity using systems biology approaches. Kotaleski and Blackwell. Nat Rev Neurosci. 2010; 11(4):239-51.