Department of Molecular Neuroscience: Computational and experimental approaches to the biophysical and biochemical mechanisms of long term memory storage, understanding the cellular and molecular events underlying the discrimination of spatio-temporal patterns by neurons
Kim 'Avrama' Blackwell is a professor in the department of Moledular Neuroscience in the Krasnow Institute of Advanced Studies.
Synchronized firing of fast-spiking interneurons is critical to maintain balanced firing between direct and indirect pathway neurons of the striatum. Damodaran S, Evans RC, Blackwell KT. J Neurophysiol. 2013 Dec 4. [Epub ahead of print]
Dynamic modulation of spike timing dependent calcium influx during cortico-striatal upstates. Evans RC, Maniar YM, Blackwell KT. J Neurophysiol. 2013 Jul 10. 110(7):1631-45.
Signaling pathways involved in striatal synaptic plasticity are sensitive to temporal pattern and exhibit spatial specificity. Kim B, Hawes SL, Gillani F, Wallace LJ, Blackwell KT. PLoS Comput Biol. 2013; 9(3):e1002953.
Colocalization of protein kinase A with adenylyl cyclase enhances protein kinase A activity during induction of long-lasting long-term-potentiation. Kim, Park, Havekes, Chay, Guercio, Oliveira, Abel, Blackwell. PLoS Comp Biol. 2011; 7: e1002084.
Modelling the molecular mechanisms of synaptic plasticity using systems biology approaches. Kotaleski and Blackwell. Nat Rev Neurosci. 2010; 11(4):239-51.